Product Name :
(+)-Penbutolol
Description:
(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.
CAS:
38363-41-6
Molecular Weight:
291.43
Formula:
C18H29NO2
Chemical Name:
(2R)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol
Smiles :
CC(C)(C)NC[C@@H](O)COC1C=CC=CC=1C1CCCC1
InChiKey:
KQXKVJAGOJTNJS-OAHLLOKOSA-N
InChi :
InChI=1S/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3/t15-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.4β-Hydroxycholesterol-d7 web
Additional information:
(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.Spesolimab Protocol 74 μM.PMID:33225870 (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.|Product information|CAS Number: 38363-41-6|Molecular Weight: 291.43|Formula: C18H29NO2|Chemical Name: (2R)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol|Smiles: CC(C)(C)NC[C@@H](O)COC1C=CC=CC=1C1CCCC1|InChiKey: KQXKVJAGOJTNJS-OAHLLOKOSA-N|InChi: InChI=1S/C18H29NO2/c1-18(2,3)19-12-15(20)13-21-17-11-7-6-10-16(17)14-8-4-5-9-14/h6-7,10-11,14-15,19-20H,4-5,8-9,12-13H2,1-3H3/t15-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (343.14 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|(+)-penbutolol on the [Ca2+]i-increase induced by LPC is concentration-dependent. (+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively).|Products are for research use only. Not for human use.|