Product Name :
Anti-TNFRSF9, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-TNFRSF9, Human antibody is designed for detecting human TNFRSF9 specifically. Based on ELISA and/or FCM, Anti-TNFRSF9, Human antibody reacts with human TNFRSF9 specifically. | Immunogen: Recombinant human TNFRSF9 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human TNFRSF9 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells.{{193275-84-2} MedChemExpress|{193275-84-2} Purity & Documentation|{193275-84-2} Purity|{193275-84-2} custom synthesis} Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival.{{1781223-80-0} web|{1781223-80-0} Purity & Documentation|{1781223-80-0} Formula|{1781223-80-0} custom synthesis} Soluble forms of CD137 may provide negative control mechanism for some immune responses.PMID:20301680
Description2 :
Anti-TNFRSF9, Human antibody is designed for detecting human TNFRSF9 specifically. Based on ELISA and/or FCM, Anti-TNFRSF9, Human antibody reacts with human TNFRSF9 specifically.
Immunogen:
Recombinant human TNFRSF9
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.