Product Name :
PKC-iota inhibitor 1
Description:
PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ℩) inhibitor with an IC50 value of 0.34 μM.
CAS:
2328094-11-5
Molecular Weight:
374.44
Formula:
C21H22N6O
Chemical Name:
2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide
Smiles :
NC1=NC=C(C=C1C(=O)NC1=CC=NC=C1)C1C=C(C=CC=1)N1CCNCC1
InChiKey:
YDMJAALVMGFGRY-UHFFFAOYSA-N
InChi :
InChI=1S/C21H22N6O/c22-20-19(21(28)26-17-4-6-23-7-5-17)13-16(14-25-20)15-2-1-3-18(12-15)27-10-8-24-9-11-27/h1-7,12-14,24H,8-11H2,(H2,22,25)(H,23,26,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{TRULI} MedChemExpress|{TRULI} YAP|{TRULI} Epigenetics|{TRULI} Biological Activity|{TRULI} In Vitro|{TRULI} custom synthesis}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ℩) inhibitor with an IC50 value of 0.{{Fura-2 AM} site|{Fura-2 AM} {Fluorescent Dye}|{Fura-2 AM} Biological Activity|{Fura-2 AM} Description|{Fura-2 AM} supplier|{Fura-2 AM} Autophagy} 34 μM.|Product information|CAS Number: 2328094-11-5|Molecular Weight: 374.44|Formula: C21H22N6O|Chemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide|Smiles: NC1=NC=C(C=C1C(=O)NC1=CC=NC=C1)C1C=C(C=CC=1)N1CCNCC1|InChiKey: YDMJAALVMGFGRY-UHFFFAOYSA-N|InChi: InChI=1S/C21H22N6O/c22-20-19(21(28)26-17-4-6-23-7-5-17)13-16(14-25-20)15-2-1-3-18(12-15)27-10-8-24-9-11-27/h1-7,12-14,24H,8-11H2,(H2,22,25)(H,23,26,28)|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (333.PMID:23522542 83 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Kwiatkowski J, et al. Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues. ACS Med Chem Lett. 2019 Feb 15;10(3):318-323.Products are for research use only. Not for human use.|