E (M) 74.8 (25.five) C-reactive protein (mg/L) 5.1 [2.0.9] GGT (IU/L) 27 [193] Total cholesterol (mmol/L) five.5 (1.1) HDL cholesterol (mmol/L) 1.4 (0.4) LDL cholesterol (mmol/L) 3.four (1.0) Triglycerides (mmol/L) 1.5 (0.9) CIMT (mm) 0.82 [0.67.02] PON1 (g/mL) 96 [7411] PONase (U/L) 184 [13120] AREase (kU/L) 107 [8232] FRAP (M) 677 [54527] TEAC (nM) 1279 [944654] Ox-LDL (ng/mL) 4408 [3143911] TBARS (nM) 2277 [1559132]Sex Guys Females 126 365 0 365 (100) 55.4 (13.three) 54.3 (13.2) 27.five (7.0) 32.eight (8.0) 94.9 (14.5) 96.9 (15.7) 0.93 (0.12) 0.87 (0.12) 138 (24) 136 (27) 84 (15) 81 (13) 6.two (2.five) 6.5 (three.1) 6.3 (1.4) six.7 (1.7) 89.5 (35.5) 69.6 (18.five) three.7 [1.five.6] 5.six [2.two.2] 31 [246] 25 [171] five.4 (1.0) 5.5 (1.1) 1.three (0.five) 1.4 (0.4) 3.four (0.9) 3.4 (1.0) 1.7 (1.1) 1.five (0.8) 0.95 [0.72.22] 0.80 [0.65.95] 88 [6905] 98 [7812] 194 [15818] 183 [12421] 91 [6504] 117 [9037] 732 [59261] 655 [53711] 1366 [1018742] 1271 [936631] 5141 [3979333] 4110 [2834484] 2042 [1527772] 2304 [1625214]Diabetes No Yes 349 142 257 (73.6) 108 (76.1) 52.five (13.4) 59.six (11.five) 30.six (7.three) 33.4 (9.5) 94.6 (16.1) 100.8 (12.9) 0.88 (0.12) 0.92 (0.12) 133 (23) 144 (31) 81 (14) 84 (14) 5.1 (0.7) 9.five (three.9) five.9 (0.four) 8.3 (2.two) 75.3 (20.0) 81.1 (42.eight) five.0 [1.9.4] 5.five [2.50.2] 25 [181] 29 [230] five.5 (1.1) 5.five (1.2) 1.4 (0.four) 1.3 (0.4) three.4 (0.9) three.4 (1.0) 1.4 (0.eight) 1.8 (1.0) 0.77 [0.65.93] 0.98 [0.77.15] 99 [7712] 91 [6607] 204 [16725] 156 [9682] 113 [9137] 90 [6315] 722 [58852] 614 [47132] 1423 [1077746] 1051 [681320] 3916 [2755138] 5885 [4602944] 1982 [1406672] 3152 [2380655]BMI Typical Overweight Obese 93 137 261 47 (50.five) 93 (67.9) 235 (90.0) 55.three (15.two) 53.6 (13.three) 54.8 (12.6) 21.five (3.1) 27.six (1.four) 37.0 (6.7) 80.five (17.1) 90.7 (8.four) 105.1 (11.two) 0.85 (0.19) 0.89 (0.09) 0.90 (0.10) 133 (31) 135 (25) 136 (25) 78 (12) 81 (12) 83 (15) 5.three (1.5) 6.6 (3.four) six.7 (three.0) five.9 (1.0) 6.8 (two.0) six.7 (1.6) 79.four (19.1) 75.0 (19.three) 73.7 (30.0) three.0 [1.0.6] two.9 [1.four.6] six.8 [3.51.1] 26 [182] 25 [183] 28 [203] five.4 (1.1) 5.7 (1.1) five.four (1.0) 1.6 (0.five) 1.three (0.4) 1.3 (0.three) 3.three (1.1) three.6 (1.0) 3.4 0.9) 1.two (0.8) 1.six (0.9) 1.6 (0.9) 0.85 [0.65.08] 0.80 [0.70.92] 0.82 [0.68.00] 107 [9215] 99 [7711] 91 [7108] 221 [18644] 198 [15626] 172 [10206] 118 [9647] 107 [8032] 98 [7723] 754 [64211] 725 [58352] 638 [52349] 1570 [1238882] 1366 [1153846] 1206 [879505] 3535 [2511747] 4337 [2859736] 4780 [3683216] 1546 [1046369] 2238 [1546115] 2533 [1924281]Oxidative Medicine and Cellular LongevityFPG: fasting plasma glucose; BMI: physique mass index; BP blood Kainate Receptor Antagonist Molecular Weight pressure; GGT: gamma glutamyl transferase; HDL: higher density lipoprotein; LDL: low density lipoprotein; CIMT: carotid intima-media thickness; PON1: paraoxonase 1; PONase: paraoxonase; AREase: arylesterase; FRAP: ferric minimizing potential of plasma; TEAC: trolox equivalent antioxidant capacity; Ox-LDL: oxidized LDL; TBARS: thiobarbituric acid reactive substances.Oxidative Medicine and Cellular LongevityCarotid intima-media KDM1/LSD1 Inhibitor MedChemExpress thickness (mm) Carotid intima-media thickness (mm) Carotid intima-media thickness (mm)2.0 1.five 1.0 0.5 0.0 40 60 80 100 120 Paraoxonase (g/mL)(a)2.0 1.5 1.0 0.5 0.0 50 100 150 200 250 Paraoxonase activity (U/L)(b)two.0 1.5 1.0 0.5 0.0 40 60 80 100 120 140 160 Arylesterase activity (kU/L)(c)Carotid intima-media thickness (mm)Carotid intima-media thickness (mm)2.0 1.five 1.0 0.five 0.0 400 600 800 1000 Ferric decreasing antioxidant power (M/L)(d)2.0 1.5 1.0 0.five 0.0 500 1000 1500 2000 ABTS TEAC (M TE/L)(e)Carotid intima-media thickness (mm)two.0 1.5 1.0 0.5 0.0 2000 4000 6000 8000 Oxydised LDL.