Peginterferon alfa-2a
Identifier : DBSNPE000235
Drug : DB00008 (Peginterferon alfa-2a)
Interacting Gene/Enzyme : Interferon lambda-3
Gene Name : IFNL3
UniProt ID : Q8IZI9
Defining Change(s) :
- C > T (rs12979860 )
Allele Name : Not Available
Genotype(s) : (T;T) / (C;T)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Lower odds of response
References :
- Muir AJ, Gong L, Johnson SG, Lee MT, Williams MS, Klein TE, Caudle KE, Nelson DR: Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for IFNL3 (IL28B) genotype and PEG interferon-alpha-based regimens. Clin Pharmacol Ther. 2014 Feb;95(2):141-6. doi: 10.1038/clpt.2013.203. Epub 2013 Oct 4. [PubMed:24096968 ]