Atazanavir
Identifier : DBSNPE000208
Drug : DB01072 (Atazanavir)
Interacting Gene/Enzyme : UDP-glucuronosyldivansferase 1-1
Gene Name : UGT1A1
UniProt ID : P22309
Defining Change(s) :
- TA pair insertion (rs3064744 )
Allele Name : UGT1A1*28
Genotype(s) : (TA;TA)
Type(s) : ADR Directly Studied
Groups : Not Available
Description : Hyperbilirubinemia
References :
- Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing. Clin Pharmacol Ther. 2016 Apr;99(4):363-9. doi: 10.1002/cpt.269. Epub 2015 Nov 9. [PubMed:26417955 ]