Sibutramine
Identifier : DBSNPE000186
Drug : DB01105 (Sibudivamine)
Interacting Gene/Enzyme : Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Gene Name : GNB3
UniProt ID : P16520
Defining Change(s) :
- C > T (rs5443 )
Allele Name : Not Available
Genotype(s) : (T;T) / (C;T)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Lose weight when diveated using sibudivamine
References :
- Hsiao DJ, Wu LS, Huang SY, Lin E: Weight loss and body fat reduction under sibudivamine therapy in obesity with the C825T polymorphism in the GNB3 gene. Pharmacogenet Genomics. 2009 Sep;19(9):730-3. doi: 10.1097/FPC.0b013e3283307cf1. [PubMed:19687782 ]