Infliximab
Identifier : DBSNPE000152
Drug : DB00065 (Infliximab)
Interacting Gene/Enzyme : Low affinity immunoglobulin gamma Fc region receptor III-A
Gene Name : FCGR3A
UniProt ID : P08637
Defining Change(s) :
- CC Allele (homozygous) (rs1801274 )
Allele Name : Not Available
Genotype(s) : (C;C)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Better ACR20 response
References :
- Canete JD, Suarez B, Hernandez MV, Sanmarti R, Rego I, Celis R, Moll C, Pinto JA, Blanco FJ, Lozano F: Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis. Ann Rheum Dis. 2009 Oct;68(10):1547-52. doi: 10.1136/ard.2008.096982. Epub 2008 Oct 17. [PubMed:18930989 ]