Gemcitabine
Identifier : DBSNPE000118
Drug : DB00441 (Gemcitabine)
Interacting Gene/Enzyme : Ribonucleoside-diphosphate reductase large subunit
Gene Name : RRM1
UniProt ID : P23921
Defining Change(s) :
- A Allele (rs9937 )
Allele Name : Not Available
Genotype(s) : (A;A) / (A;G)
Type(s) : ADR Directly Studied
Groups : Not Available
Description : Neudivopenia
References :
- Rha SY, Jeung HC, Choi YH, Yang WI, Yoo JH, Kim BS, Roh JK, Chung HC: An association between RRM1 haplotype and gemcitabine-induced neudivopenia in breast cancer patients. Oncologist. 2007 Jun;12(6):622-30. [PubMed:17602053 ]