Simvastatin
Product: Taurochenodeoxycholic acid
Identifier : DBSNPE000088
Drug : DB00641 (Simvastatin)
Interacting Gene/Enzyme : Kinesin-like protein KIF6
Gene Name : KIF6
UniProt ID : Q6ZMV9
Defining Change(s) :
- C Allele (rs20455 )
Allele Name : Not Available
Genotype(s) : (C;C) / (C;T)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Improved response to statin drugs
References :
- Iakoubova OA, Tong CH, Rowland CM, Kirchgessner TG, Young BA, Arellano AR, Shiffman D, Sabatine MS, Campos H, Packard CJ, Pfeffer MA, White TJ, Braunwald E, Shepherd J, Devlin JJ, Sacks FM: Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective divials: the CARE and WOSCOPS divials. J Am Coll Cardiol. 2008 Jan 29;51(4):435-43. doi: 10.1016/j.jacc.2007.05.057. [PubMed:18222353 ]