Product Name :
PD1-PDL1-IN 1
Description:
PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator.
CAS:
2005454-12-4
Molecular Weight:
385.38
Formula:
C14H23N7O6
Chemical Name:
(2S,3R)-2-([(1S)-2-carbamoyl-1-[3-(piperazin-1-yl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoylamino)-3-hydroxybutanoic acid
Smiles :
C[C@@H](O)[C@H](NC(=O)N[C@@H](CC(N)=O)C1=NC(=NO1)N1CCNCC1)C(O)=O
InChiKey:
RKAIKBRLPZSBRN-WEDXCCLWSA-N
InChi :
InChI=1S/C14H23N7O6/c1-7(22)10(12(24)25)18-14(26)17-8(6-9(15)23)11-19-13(20-27-11)21-4-2-16-3-5-21/h7-8,10,16,22H,2-6H2,1H3,(H2,15,23)(H,24,25)(H2,17,18,26)/t7-,8+,10+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor.Capmatinib Technical Information PD1-PDL1-IN 1 is useful as immune modulator.|Product information|CAS Number: 2005454-12-4|Molecular Weight: 385.38|Formula: C14H23N7O6|Chemical Name: (2S,3R)-2-([(1S)-2-carbamoyl-1-[3-(piperazin-1-yl)-1,2,4-oxadiazol-5-yl]ethyl]carbamoylamino)-3-hydroxybutanoic acid|Smiles: C[C@@H](O)[C@H](NC(=O)N[C@@H](CC(N)=O)C1=NC(=NO1)N1CCNCC1)C(O)=O|InChiKey: RKAIKBRLPZSBRN-WEDXCCLWSA-N|InChi: InChI=1S/C14H23N7O6/c1-7(22)10(12(24)25)18-14(26)17-8(6-9(15)23)11-19-13(20-27-11)21-4-2-16-3-5-21/h7-8,10,16,22H,2-6H2,1H3,(H2,15,23)(H,24,25)(H2,17,18,26)/t7-,8+,10+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Combretastatin A4 Cell Cycle/DNA Damage |Shelf Life: ≥12 months if stored properly.PMID:31643182 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance.|Products are for research use only. Not for human use.|