Product Name :
Pseudolaric Acid B
Description:
Pseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi Gorden (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest. Pseudolaric Acid B induces autophagy.
CAS:
82508-31-4
Molecular Weight:
432.46
Formula:
C23H28O8
Chemical Name:
(2E, 4E)-5-[(1R, 7S, 8S, 9R)-7-(acetyloxy)-4-(methoxycarbonyl)-9-methyl-11-oxo-10-oxatricyclo[6.3.2.0, ]tridec-3-en-9-yl]-2-methylpenta-2, 4-dienoic acid
Smiles :
C[C@]1(/C=C/C=C(\C)/C(O)=O)OC(=O)[C@]23CC=C(CC[C@]2(OC(C)=O)[C@H]1CC3)C(=O)OC
InChiKey:
VDGOFNMYZYBUDT-YDRCMHEVSA-N
InChi :
InChI=1S/C23H28O8/c1-14(18(25)26)6-5-10-21(3)17-9-12-22(20(28)31-21)11-7-16(19(27)29-4)8-13-23(17,22)30-15(2)24/h5-7,10,17H,8-9,11-13H2,1-4H3,(H,25,26)/b10-5+,14-6+/t17-,21+,22+,23-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Pseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi Gorden (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest.{{Nilotinib} site|{Nilotinib} Autophagy|{Nilotinib} Biological Activity|{Nilotinib} In Vivo|{Nilotinib} supplier|{Nilotinib} Epigenetic Reader Domain} Pseudolaric Acid B induces autophagy.{{Neomycin} medchemexpress|{Neomycin} Bacterial|{Neomycin} Biological Activity|{Neomycin} Data Sheet|{Neomycin} manufacturer|{Neomycin} Autophagy} |Product information|CAS Number: 82508-31-4|Molecular Weight: 432.PMID:33089758 46|Formula: C23H28O8|Chemical Name: (2E, 4E)-5-[(1R, 7S, 8S, 9R)-7-(acetyloxy)-4-(methoxycarbonyl)-9-methyl-11-oxo-10-oxatricyclo[6.3.2.0, ]tridec-3-en-9-yl]-2-methylpenta-2, 4-dienoic acid|Smiles: C[C@]1(/C=C/C=C(\C)/C(O)=O)OC(=O)[C@]23CC=C(CC[C@]2(OC(C)=O)[C@H]1CC3)C(=O)OC|InChiKey: VDGOFNMYZYBUDT-YDRCMHEVSA-N|InChi: InChI=1S/C23H28O8/c1-14(18(25)26)6-5-10-21(3)17-9-12-22(20(28)31-21)11-7-16(19(27)29-4)8-13-23(17,22)30-15(2)24/h5-7,10,17H,8-9,11-13H2,1-4H3,(H,25,26)/b10-5+,14-6+/t17-,21+,22+,23-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 125 mg/mL (289.04 mM)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Zhou BN, et al. Some progress on the chemistry of natural bioactive terpenoids from Chinese medicinal plants. Mem Inst Oswaldo Cruz. 1991;86 Suppl 2:219-26.Wang WC, et al. [Endocrine activity of pseudolaric acids A and B and their effects on sex hormones, prostaglandins, uteri, and fetuses]. Zhongguo Yao Li Xue Bao. 1991 Mar;12(2):187-90.Wei N, et al. The immunosuppressive activity of pseudolaric acid B on T lymphocytes in vitro. Phytother Res. 2013 Jul;27(7):980-5.Products are for research use only. Not for human use.|