Product Name :
4-[(6-aminohexyl)oxy]-2-(2, 6-dioxopiperidin-3-yl)-2, 3-dihydro-1H-isoindole-1, 3-dione hydrochloride

Description:
Thalidomide-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET.

CAS:
2245697-88-3

Molecular Weight:
409.86

Formula:
C19H24ClN3O5

Chemical Name:
Thalidomide-O-C6-NH2 hydrochloride

Smiles :
Cl.NCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey:
HYHUBACBCPALHK-UHFFFAOYSA-N

InChi :
InChI=1S/C19H23N3O5.ClH/c20-10-3-1-2-4-11-27-14-7-5-6-12-16(14)19(26)22(18(12)25)13-8-9-15(23)21-17(13)24;/h5-7,13H,1-4,8-11,20H2,(H,21,23,24);1H

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Naptumomab} MedChemExpress|{Naptumomab} Purity & Documentation|{Naptumomab} In stock|{Naptumomab} manufacturer|{Naptumomab} Epigenetic Reader Domain}

Shelf Life:
≥360 days if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Thalidomide-O-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET.{{ITE} MedChemExpress|{ITE} Immunology/Inflammation|{ITE} Purity & Documentation|{ITE} References|{ITE} custom synthesis|{ITE} Autophagy} |Product information|CAS Number: 2245697-88-3|Molecular Weight: 409.PMID:33075241 86|Formula: C19H24ClN3O5|Chemical Name: Thalidomide-O-C6-NH2 hydrochloride|Smiles: Cl.NCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O|InChiKey: HYHUBACBCPALHK-UHFFFAOYSA-N|InChi: InChI=1S/C19H23N3O5.ClH/c20-10-3-1-2-4-11-27-14-7-5-6-12-16(14)19(26)22(18(12)25)13-8-9-15(23)21-17(13)24;/h5-7,13H,1-4,8-11,20H2,(H,21,23,24);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 83.33 mg/mL (203.31 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Erb MA, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. 2017 Mar 9;543(7644):270-274.Products are for research use only. Not for human use.|

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