Product Name :
BACE1-IN-1
Description:
BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
CAS:
1310347-50-2
Molecular Weight:
389.33
Formula:
C18H14F3N5O2
Chemical Name:
N-{3-[(4R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide
Smiles :
C[C@@]1(N=C(N)OCC1(F)F)C1=CC(=CC=C1F)NC(=O)C1C=CC(=CN=1)C#N
InChiKey:
DVMUZHLUMHPCGZ-QGZVFWFLSA-N
InChi :
InChI=1S/C18H14F3N5O2/c1-17(18(20,21)9-28-16(23)26-17)12-6-11(3-4-13(12)19)25-15(27)14-5-2-10(7-22)8-24-14/h2-6,8H,9H2,1H3,(H2,23,26)(H,25,27)/t17-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.{{Crystal Violet} site|{Crystal Violet} Influenza Virus|{Crystal Violet} Technical Information|{Crystal Violet} In stock|{Crystal Violet} custom synthesis|{Crystal Violet} Autophagy} |Product information|CAS Number: 1310347-50-2|Molecular Weight: 389.{{Rhodamine B} MedChemExpress|{Rhodamine B} {Fluorescent Dye}|{Rhodamine B} Technical Information|{Rhodamine B} Description|{Rhodamine B} supplier|{Rhodamine B} Autophagy} 33|Formula: C18H14F3N5O2|Chemical Name: N-{3-[(4R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide|Smiles: C[C@@]1(N=C(N)OCC1(F)F)C1=CC(=CC=C1F)NC(=O)C1C=CC(=CN=1)C#N|InChiKey: DVMUZHLUMHPCGZ-QGZVFWFLSA-N|InChi: InChI=1S/C18H14F3N5O2/c1-17(18(20,21)9-28-16(23)26-17)12-6-11(3-4-13(12)19)25-15(27)14-5-2-10(7-22)8-24-14/h2-6,8H,9H2,1H3,(H2,23,26)(H,25,27)/t17-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23558135 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|