Product Name :
Irbesartan
Description:
Irbesartan, also known as BMS-186295, is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.
CAS:
138402-11-6
Molecular Weight:
428.53
Formula:
C25H28N6O
Chemical Name:
2-butyl-3-{[2′-(1H-1,2,3,4-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
Smiles :
CCCCC1=NC2(CCCC2)C(=O)N1CC1C=CC(=CC=1)C1=CC=CC=C1C1NN=NN=1
InChiKey:
YOSHYTLCDANDAN-UHFFFAOYSA-N
InChi :
InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Irbesartan, also known as BMS-186295, is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.{{Soticlestat} site|{Soticlestat} Metabolic Enzyme/Protease|{Soticlestat} Technical Information|{Soticlestat} Purity|{Soticlestat} manufacturer|{Soticlestat} Epigenetics} It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium.{{(-)-(S)-Equol} site|{(-)-(S)-Equol} Estrogen Receptor/ERR|{(-)-(S)-Equol} Technical Information|{(-)-(S)-Equol} References|{(-)-(S)-Equol} supplier|{(-)-(S)-Equol} Autophagy} Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle.PMID:23812309 |Product information|CAS Number: 138402-11-6|Molecular Weight: 428.53|Formula: C25H28N6O|Chemical Name: 2-butyl-3-{[2′-(1H-1,2,3,4-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one|Smiles: CCCCC1=NC2(CCCC2)C(=O)N1CC1C=CC(=CC=1)C1=CC=CC=C1C1NN=NN=1|InChiKey: YOSHYTLCDANDAN-UHFFFAOYSA-N|InChi: InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|