Product Name :
1-Naphthyl PP1
Description:
1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
CAS:
221243-82-9
Molecular Weight:
317.39
Formula:
C19H19N5
Chemical Name:
1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Smiles :
CC(C)(C)N1N=C(C2=C(N)N=CN=C12)C1=CC=CC2=CC=CC=C21
InChiKey:
XSHQBIXMLULFEV-UHFFFAOYSA-N
InChi :
InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{RLY-2608} site|{RLY-2608} PI3K|{RLY-2608} Purity & Documentation|{RLY-2608} In Vitro|{RLY-2608} supplier|{RLY-2608} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Inebilizumab} web|{Inebilizumab} Antibody-drug Conjugate/ADC Related|{Inebilizumab} Protocol|{Inebilizumab} Data Sheet|{Inebilizumab} custom synthesis|{Inebilizumab} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23415682
Additional information:
1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.|Product information|CAS Number: 221243-82-9|Molecular Weight: 317.39|Formula: C19H19N5|Synonym:|1-NA-PP 1|Chemical Name: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine|Smiles: CC(C)(C)N1N=C(C2=C(N)N=CN=C12)C1=CC=CC2=CC=CC=C21|InChiKey: XSHQBIXMLULFEV-UHFFFAOYSA-N|InChi: InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|