December, 2024 | PI3KInhibitorpi3kinhibitor

PTN57491

stevenboivie December 21, 2024 0 Comments

Product Name : PTN57491Description:PTN57491 is an key intermediate chemical to synthesize antiviral drugs remdesivir and GS441524.CAS: 1355357-49-1Molecular Weight:561.63Formula: C33H31N5O4Chemical Name: (2R,3R,4R,5R)-2-(4-Aminopyrrolotriazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carbonitrileSmiles : NC1=NC=NN2C(=CC=C21)1(C#N)O(COCC2C=CC=CC=2)(OCC2C=CC=CC=2)1OCC1C=CC=CC=1InChiKey: PJXBLWLWNWGFJO-TXLSGFARSA-NInChi : InChI=1S/C33H31N5O4/c34-22-33(29-17-16-27-32(35)36-23-37-38(27)29)31(41-20-26-14-8-3-9-15-26)30(40-19-25-12-6-2-7-13-25)28(42-33)21-39-18-24-10-4-1-5-11-24/h1-17,23,28,30-31H,18-21H2,(H2,35,36,37)/t28-,30-,31-,33+/m1/s1Purity: ≥98% (or refer to…

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FIDAS-5

stevenboivie December 21, 2024 0 Comments

Product Name : FIDAS-5Description:FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding.…

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Hypocrellin A

stevenboivie December 20, 2024 0 Comments

Product Name : Hypocrellin ADescription:Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising…

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PKC-iota inhibitor 1

stevenboivie December 20, 2024 0 Comments

Product Name : PKC-iota inhibitor 1Description:PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ℩) inhibitor with an IC50 value of 0.34 μM.CAS: 2328094-11-5Molecular Weight:374.44Formula: C21H22N6OChemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamideSmiles…

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(-)-Narwedine

stevenboivie December 19, 2024 0 Comments

Product Name : (-)-NarwedineDescription:(-)-Narwedine is a cholinesterase (AChE) inhibitor for the treatment of mild to moderate Alzheimer's disease.CAS: 510-77-0Molecular Weight:285.34Formula: C17H19NO3Chemical Name: (4aS,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurobenzazepin-6-oneSmiles : COC1=CC=C2CN(C)CC34C=CC(=O)C3OC1=C42InChiKey: QENVUHCAYXAROT-YOEHRIQHSA-NInChi : InChI=1S/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/m0/s1Purity: ≥98% (or…

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Verteporfin (Visudyne) — YAP Inhibitor

stevenboivie December 18, 2024 0 Comments

Product Name : Verteporfin (Visudyne) --- YAP InhibitorDescription:Verteporfin (Visudyne) is a potent and selective YAP inhibitor, disrupts YAP-TEAD interactions and enhances trypsin cleavage of YAP with EC50 ~100 nM. It…

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EPZ-5676 — DOT1L inhibitor

stevenboivie December 17, 2024 0 Comments

Product Name : EPZ-5676 --- DOT1L inhibitorDescription:EPZ-5676 is a highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.…

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Nav1.8-IN-2

stevenboivie December 17, 2024 0 Comments

Product Name : Nav1.8-IN-2Description:Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with anICsovalue of 0.4 nM.Nav1.8-IN-2 can be used for researching pain disorders. cough disorders, and acute and chronic itch…

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trans-R-138727MP

stevenboivie December 16, 2024 0 Comments

Product Name : trans-R-138727MPDescription:trans-R-138727MP (Prasugrel metabolite R-138727MP) is the active metabolite derivative of Prasugrel (HY-15284). Prasugrel, a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent…

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(2R)-2-Hydroxypropanoate sodium

stevenboivie December 16, 2024 0 Comments

Product Name : (2R)-2-Hydroxypropanoate sodiumDescription:(2R)-2-Hydroxypropanoate sodium is an endogenous metabolite.CAS: 920-49-0Molecular Weight:112.06Formula: C3H5NaO3Chemical Name: sodium (2R)-2-hydroxypropanoateSmiles : .C(O)C()=OInChiKey: NGSFWBMYFKHRBD-HSHFZTNMSA-MInChi : InChI=1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m1./s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition:…

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