Product Name :
UNC0224
Description:
NC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM.4 Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM.
CAS:
1197196-48-7
Molecular Weight:
485.67
Formula:
C26H43N7O2
Chemical Name:
7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Smiles :
CN(C)CCCOC1=CC2=NC(=NC(NC3CCN(C)CC3)=C2C=C1OC)N1CCCN(C)CC1
InChiKey:
XIVUGRBSBIXXJE-UHFFFAOYSA-N
InChi :
InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H,6-17H2,1-5H3,(H,27,28,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NC0224 is a potent and selective G9a HMTase inhibitor, exhibiting an IC50 value of 15 nM.4 Isothermal titration calorimetry revealed UNC0224 binds to G9a with a Kd value of 29 nM.|Product information|CAS Number: 1197196-48-7|Molecular Weight: 485.67|Formula: C26H43N7O2|Chemical Name: 7-[3-(dimethylamino)propoxy]-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine|Smiles: CN(C)CCCOC1=CC2=NC(=NC(NC3CCN(C)CC3)=C2C=C1OC)N1CCCN(C)CC1|InChiKey: XIVUGRBSBIXXJE-UHFFFAOYSA-N|InChi: InChI=1S/C26H43N7O2/c1-30(2)10-7-17-35-24-19-22-21(18-23(24)34-5)25(27-20-8-13-32(4)14-9-20)29-26(28-22)33-12-6-11-31(3)15-16-33/h18-20H,6-17H2,1-5H3,(H,27,28,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{N-Desmethylclozapine} web|{N-Desmethylclozapine} GPCR/G Protein|{N-Desmethylclozapine} Purity & Documentation|{N-Desmethylclozapine} In stock|{N-Desmethylclozapine} custom synthesis|{N-Desmethylclozapine} Epigenetics} |Shelf Life: ≥360 days if stored properly.{{IL-4 Protein, Mouse} medchemexpress|{IL-4 Protein, Mouse} Technical Information|{IL-4 Protein, Mouse} In Vitro|{IL-4 Protein, Mouse} custom synthesis|{IL-4 Protein, Mouse} Epigenetic Reader Domain} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24818938 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|