Product Name :
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine
Description:
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
175724-30-8
Molecular Weight:
505.64
Formula:
C25H47NO9
Chemical Name:
tert-butyl 3-{2-amino-3-[3-(tert-butoxy)-3-oxopropoxy]-2-{[3-(tert-butoxy)-3-oxopropoxy]methyl}propoxy}propanoate
Smiles :
CC(C)(C)OC(=O)CCOCC(N)(COCCC(=O)OC(C)(C)C)COCCC(=O)OC(C)(C)C
InChiKey:
KPXODPHVWBQJEG-UHFFFAOYSA-N
InChi :
InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 175724-30-8|Molecular Weight: 505.64|Formula: C25H47NO9|Chemical Name: tert-butyl 3-{2-amino-3-[3-(tert-butoxy)-3-oxopropoxy]-2-{[3-(tert-butoxy)-3-oxopropoxy]methyl}propoxy}propanoate|Smiles: CC(C)(C)OC(=O)CCOCC(N)(COCCC(=O)OC(C)(C)C)COCCC(=O)OC(C)(C)C|InChiKey: KPXODPHVWBQJEG-UHFFFAOYSA-N|InChi: InChI=1S/C25H47NO9/c1-22(2,3)33-19(27)10-13-30-16-25(26,17-31-14-11-20(28)34-23(4,5)6)18-32-15-12-21(29)35-24(7,8)9/h10-18,26H2,1-9H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Mosunetuzumab} MedChemExpress|{Mosunetuzumab} Immunology/Inflammation|{Mosunetuzumab} Technical Information|{Mosunetuzumab} References|{Mosunetuzumab} supplier|{Mosunetuzumab} Autophagy} |Shelf Life: ≥12 months if stored properly.{{15-Deoxy-Δ-12,14-prostaglandin J2} site|{15-Deoxy-Δ-12,14-prostaglandin J2} Metabolic Enzyme/Protease|{15-Deoxy-Δ-12,14-prostaglandin J2} Technical Information|{15-Deoxy-Δ-12,14-prostaglandin J2} In Vitro|{15-Deoxy-Δ-12,14-prostaglandin J2} supplier|{15-Deoxy-Δ-12,14-prostaglandin J2} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24463635 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|