Product Name :
IVHD-valtrate
Description:
IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research.
CAS:
28325-56-6
Molecular Weight:
540.60
Formula:
C27H40O11
Chemical Name:
[(1S,4aR,6S,7R,7aS)-6-(acetyloxy)-4a-hydroxy-1-[(3-methylbutanoyl)oxy]-4a,5,6,7a-tetrahydro-1H-spiro[cyclopenta[c]pyran-7,2′-oxiran]-4-yl]methyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate
Smiles :
CC(=O)O[C@H]1C[C@@]2(O)[C@H]([C@@H](OC=C2COC(=O)C(OC(=O)CC(C)C)C(C)C)OC(=O)CC(C)C)[C@]21CO2
InChiKey:
QPMVBTMUWDUUTJ-KZYULCMASA-N
InChi :
InChI=1S/C27H40O11/c1-14(2)8-20(29)37-22(16(5)6)24(31)33-11-18-12-34-25(38-21(30)9-15(3)4)23-26(18,32)10-19(36-17(7)28)27(23)13-35-27/h12,14-16,19,22-23,25,32H,8-11,13H2,1-7H3/t19-,22?,23-,25-,26-,27+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research.|Product information|CAS Number: 28325-56-6|Molecular Weight: 540.60|Formula: C27H40O11|Chemical Name: [(1S,4aR,6S,7R,7aS)-6-(acetyloxy)-4a-hydroxy-1-[(3-methylbutanoyl)oxy]-4a,5,6,7a-tetrahydro-1H-spiro[cyclopenta[c]pyran-7,2′-oxiran]-4-yl]methyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate|Smiles: CC(=O)O[C@H]1C[C@@]2(O)[C@H]([C@@H](OC=C2COC(=O)C(OC(=O)CC(C)C)C(C)C)OC(=O)CC(C)C)[C@]21CO2|InChiKey: QPMVBTMUWDUUTJ-KZYULCMASA-N|InChi: InChI=1S/C27H40O11/c1-14(2)8-20(29)37-22(16(5)6)24(31)33-11-18-12-34-25(38-21(30)9-15(3)4)23-26(18,32)10-19(36-17(7)28)27(23)13-35-27/h12,14-16,19,22-23,25,32H,8-11,13H2,1-7H3/t19-,22?,23-,25-,26-,27+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Floxuridine} web|{Floxuridine} Nucleoside Antimetabolite/Analog|{Floxuridine} Technical Information|{Floxuridine} In Vitro|{Floxuridine} supplier|{Floxuridine} Autophagy} |Shelf Life: ≥12 months if stored properly.{{L-Asparaginase} medchemexpress|{L-Asparaginase} Cell Cycle/DNA Damage|{L-Asparaginase} Purity & Documentation|{L-Asparaginase} Formula|{L-Asparaginase} custom synthesis|{L-Asparaginase} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23907051 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|IVHD-valtrate inhibits the growth and proliferation of the A2780 and OVCAR-3 ovarian cancer cell lines in a concentration-dependent manner. IVHD-valtrate results in a relatively low cytotoxicity to immortalized non-tumorigenic human ovarian surface epithelial cells (IOSE-144).|Products are for research use only. Not for human use.|