Product Name : BD-1047 DihydrobromideDescription:BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors shows antipsychotic activity in animal models predictive of efficacy in schizophreniaCAS: 138356-21-5Molecular Weight:437.04Formula: C13H22Br2Cl2N2Chemical Name: N1-(3,…
Product Name : PTN57491Description:PTN57491 is an key intermediate chemical to synthesize antiviral drugs remdesivir and GS441524.CAS: 1355357-49-1Molecular Weight:561.63Formula: C33H31N5O4Chemical Name: (2R,3R,4R,5R)-2-(4-Aminopyrrolotriazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-carbonitrileSmiles : NC1=NC=NN2C(=CC=C21)1(C#N)O(COCC2C=CC=CC=2)(OCC2C=CC=CC=2)1OCC1C=CC=CC=1InChiKey: PJXBLWLWNWGFJO-TXLSGFARSA-NInChi : InChI=1S/C33H31N5O4/c34-22-33(29-17-16-27-32(35)36-23-37-38(27)29)31(41-20-26-14-8-3-9-15-26)30(40-19-25-12-6-2-7-13-25)28(42-33)21-39-18-24-10-4-1-5-11-24/h1-17,23,28,30-31H,18-21H2,(H2,35,36,37)/t28-,30-,31-,33+/m1/s1Purity: ≥98% (or refer to…
Product Name : FIDAS-5Description:FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding.…
Product Name : Hypocrellin ADescription:Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising…
Product Name : PKC-iota inhibitor 1Description:PKC-iota inhibitor 1 (compound 19) is a protein kinase C-iota (PKC-ι ℩) inhibitor with an IC50 value of 0.34 μM.CAS: 2328094-11-5Molecular Weight:374.44Formula: C21H22N6OChemical Name: 2-amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamideSmiles…
Product Name : (-)-NarwedineDescription:(-)-Narwedine is a cholinesterase (AChE) inhibitor for the treatment of mild to moderate Alzheimer's disease.CAS: 510-77-0Molecular Weight:285.34Formula: C17H19NO3Chemical Name: (4aS,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofurobenzazepin-6-oneSmiles : COC1=CC=C2CN(C)CC34C=CC(=O)C3OC1=C42InChiKey: QENVUHCAYXAROT-YOEHRIQHSA-NInChi : InChI=1S/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/m0/s1Purity: ≥98% (or…
Product Name : Verteporfin (Visudyne) --- YAP InhibitorDescription:Verteporfin (Visudyne) is a potent and selective YAP inhibitor, disrupts YAP-TEAD interactions and enhances trypsin cleavage of YAP with EC50 ~100 nM. It…
Product Name : EPZ-5676 --- DOT1L inhibitorDescription:EPZ-5676 is a highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.…
Product Name : Nav1.8-IN-2Description:Nav1.8-IN-2 (compound 35A) is a potent Nav1.8 inhibitor with anICsovalue of 0.4 nM.Nav1.8-IN-2 can be used for researching pain disorders. cough disorders, and acute and chronic itch…
Product Name : trans-R-138727MPDescription:trans-R-138727MP (Prasugrel metabolite R-138727MP) is the active metabolite derivative of Prasugrel (HY-15284). Prasugrel, a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent…