SPE group when compared with several SSPE group (21.6 vs 6.9 , P = 0.166). Proportion of patients with reduce extremity DVT was not significantly different in various SSPE group in comparison with solitary SSPE group (96.6 vs 83.eight , P = 0.124). No DVT inside the axial iliac-common femoral venous segment was found (a single DVT in internal iliac vein) in solitary SSPE group versus 4 in many SSPE group (P = 0.033). Thrombus burden assessed by a specially made scoring method (Table 2) revealed more comprehensive DVT burden in several SSPE in comparison to solitary SSPE group (five.7 vs 2.four, P = 0.008). VTE recurrence, big bleeding, clinically relevant non-major bleeding, and CDK4 Inhibitor Compound mortality was not diverse in SSPE with DVT examine to these with out DVT (information not shown).878 of|ABSTRACTTable 1 Extremity deep vein thrombosis (DVT) place and burden in sufferers with solitary versus multiple subsegmental pulmonary emboli (SSPE).DVT Place Iliac or Frequent Femoral Veins, n ( ) Prevalent Iliac, External Iliac, or Common Femoral Veins, n ( ) Femoral or Popliteal Veins, n ( ) Calf Veins, n ( ) Reduced Extremity Veins, n ( ) Upper Extremity Veins, n ( ) Upper or Decrease Extremity Veins, n ( ) Extremity DVT burden score: Imply (SD) b, Rangea bSolitary N = 37 1 (two.7 ) 0 (0.0 ) 13 (35.1 ) 25 (67.6 ) 31 (83.8 ) 8 (21.6 ) 37 (100 )Numerous N = 29 5 (17.2 ) four (13.8 ) 12 (41.four ) 22 (75.9 ) 28 (96.6 ) 2 (6.9 ) 29 (100 )Total N = 66 six (9.1 ) 4 (six.1 ) 25 (37.9 ) 47 (71.two ) 59 (89.4 ) 10 (15.two ) 66 (100 )P-valuea 0.079 0.033 0.620 0.586 0.124 0.166 0.170 0.2.four (two.0) 0.51.5.7 (6.6) 0.50.three.8 (four.9) 0.50.P-values outcome from analysis of variance for continuous variables and Chi square test for categorical variables SD = standard deviationTable 2 Extremity deep vein thrombosis (DVT) burden scoring system.DVT Location Iliac (Prevalent, External, Internal) Innominate, Subclavian, Typical Femoral, Popliteal Femoral divided into Proximal, Middle, Distal 100 Vein Involvement 5 three Each and every segment = 3 100 Vein Involvement Axillary, Brachial, Internal Jugular, Tibial (Anterior, Posterior), Peroneal, Soleal, Gastrocnemius C Superficial Vein Thrombus Extending to Deep Vein Place 1 one hundred Involvement 0.five 509 Involvement three 2 50 Involvement 2Sapheno-femoral junction = two Sapheno-Popliteal junction =cIf duplicated calf vein, every single vein with DVT was scored per systemConclusions: Extremity thrombus burden is substantially larger in several SSPE compared to solitary SSPE. DVT involving the axial iliac-common femoral segment is linked with various SSPE. Upper and reduce extremity DVT have been evenly distributed involving groups.PB1196|The Roles of Individual and Neighborhood Revenue on Regional and Racial Variations in Threat of Venous Thromboembolism inside the Usa: The Motives for Geographic and Racial Differences in Stroke Study (REGARDS) J. Munger1; K. Wilkinson2; I. Koh2; L. Long3; G. Lovasi4; L. McClure 4; J. Brown4; G. Howard3; V. Howard3; T. Plante1,5; M. Cushman2,5; N. Zakai2,University of Vermont, Larner College of Medicine, Burlington, UnitedStates; 2Department of CD40 Activator Formulation Pathology Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, United states;College of Public Wellness in the University of Alabama at Birmingham,Birmingham, United states of america; 4Dornsife School of Public well being at Drexel University, Philadelphia, United states; 5Department of Medicine, Larner College of Medicine in the University of Vermont, Burlington, United states of america Background: Within the Usa (U.S.), Bla