Rituximab
Identifier : DBSNPE000160
Drug : DB00073 (Rituximab)
Interacting Gene/Enzyme : Low affinity immunoglobulin gamma Fc region receptor III-A
Gene Name : FCGR3A
UniProt ID : P08637
Defining Change(s) :
- A > C (rs396991 )
Allele Name : Not Available
Genotype(s) : (G;G) / (G;T)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Better response to drug therapy (compared to allele A)
References :
- Kim DH, Jung HD, Kim JG, Lee JJ, Yang DH, Park YH, Do YR, Shin HJ, Kim MK, Hyun MS, Sohn SK: FCGR3A gene polymorphisms may correlate with response to frontline R-CHOP therapy for diffuse large B-cell lymphoma. Blood. 2006 Oct 15;108(8):2720-5. Epub 2006 Apr 11. [PubMed:16609067 ]