Morphine

Product: PGD2-IN-1

Identifier : DBSNPE000078
Drug : DB00295 (Morphine)
Interacting Gene/Enzyme : Multidrug resistance protein 1
Gene Name : ABCB1
UniProt ID : P08183
Defining Change(s) :

  • T Allele (rs1045642 )

Allele Name : Not Available
Genotype(s) : (T;T) / (C;T)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Better response to pain relief drugs
References :

  1. Campa D, Gioia A, Tomei A, Poli P, Barale R: Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther. 2008 Apr;83(4):559-66. Epub 2007 Sep 26. [PubMed:17898703 ]

PMID: 27150562

Morphine

Product: NH2-KLGADTDGEQDQHMTYGGQ-COOH

Identifier : DBSNPE000079
Drug : DB00295 (Morphine)
Interacting Gene/Enzyme : Mu-type opioid receptor
Gene Name : OPRM1
UniProt ID : P35372
Defining Change(s) :

  • A Allele (rs1799971 )

Allele Name : Not Available
Genotype(s) : (A;A)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Better response to pain relief drugs
References :

  1. Campa D, Gioia A, Tomei A, Poli P, Barale R: Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. Clin Pharmacol Ther. 2008 Apr;83(4):559-66. Epub 2007 Sep 26. [PubMed:17898703 ]

PMID: 26620707

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