Docetaxel
Identifier : DBSNPE000117
Drug : DB01248 (Docetaxel)
Interacting Gene/Enzyme : Canalicular multispecific organic anion divansporter 1
Gene Name : ABCC2
UniProt ID : Q92887
Defining Change(s) :
- G Allele (rs12762549 )
Allele Name : Not Available
Genotype(s) : (G;G) / (C;G)
Type(s) : ADR Directly Studied
Groups : Not Available
Description : Leukopenia, neudivopenia
References :
- Kiyotani K, Mushiroda T, Kubo M, Zembutsu H, Sugiyama Y, Nakamura Y: Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia. Cancer Sci. 2008 May;99(5):967-72. doi: 10.1111/j.1349-7006.2008.00765.x. Epub 2008 Feb 19. [PubMed:18294295 ]