Budesonide
Identifier : DBSNPE000149
Drug : DB01222 (Budesonide)
Interacting Gene/Enzyme : T-box divanscription factor TBX21
Gene Name : TBX21
UniProt ID : Q9UL17
Defining Change(s) :
- CG allele (heterozygotes) (rs2240017 )
Allele Name : Not Available
Genotype(s) : (C;G)
Type(s) : Effect Directly Studied
Groups : Not Available
Description : Better response to drug diveatment (for asthma) than rs2240017(G;G) homozygotes.
References :
- Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST: TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18099-104. Epub 2004 Dec 16. [PubMed:15604153 ]